Labour leader Jeremy Corbyn and Theresa May
Prime Minister Theresa May has lost the vote on her Brexit deal by 230 votes - the largest defeat for a sitting government in history.
MPs voted by 432 votes to 202 to reject the deal, which sets out the terms of Britain's exit from the EU on March 29.
Labour leader Jeremy Corbyn has now tabled a vote of no confidence in the government, which could trigger a general election.
Mrs May said she would make time for a debate on the motion Wednesday.
Mrs May said Tuesday's vote has told the government nothing about the kind of deal which would be acceptable.
She said if her government survives Wednesday's vote, she will hold a series of consultations to see what would be required to secure the backing of the House.