At least 17 Palestinians have been wounded in clashes in the Gaza Strip and across the occupied West Bank, during protests against US President Donald Trump's recognition of Jerusalem as Israel's capital.
One person is in critical condition.
Mr. Trump's announcement - met with worldwide dismay - reversed decades of US policy on the sensitive issue.
Israel deployed hundreds of extra troops in the West Bank as Palestinians went on strike and took to the streets.
Protesters set tyres alight and threw stones, and Israeli troops fired tear gas, rubber bullets and live bullets.
According to Reuters news agency, in Gaza, Palestinians threw stones across the border fence at Israeli soldiers who responded with live fire.
Many of Washington's closest allies have said they disagree with the move, and both the UN Security Council and the Arab League will meet in coming days to decide their response.